Dr. Farag and Dr. Abu Zaid lead the Stem Cell Transplant and Cellular Therapy Institute

Stem Cell Transplant and Cellular Therapy Institute

To help bring innovative care close to home, we’ve enhanced the continuum of cancer care we provide within our network.

Community Health Network MD Anderson Cancer Center’s Stem Cell Transplant and Cellular Therapy Institute treats a variety of cancer and non-cancer conditions effectively and efficiently — applying state-of-the-art technologies in dedicated facilities backed by an experienced team.

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Welcome From the Team

Stem cell transplant team

We follow a team approach to treating malignant and nonmalignant blood disorders. The Institute brings together physicians, advanced practice providers, quality specialists, coordinators and nurses with extensive experience in stem cell transplant and cellular therapy. Through our multidisciplinary approach, we provide comprehensive services to support patients before, during and after their transplant. We also push the frontiers of stem cell therapy and treatment through cutting-edge research.

Celebrating Our First Stem Cell Transplant

Community Health Network MD Anderson Cancer Center marks the official launch of its Stem Cell Transplant and Cellular Therapy Institute, admitting its first stem cell transplant patients as a program.

Meet Dr. Farag

Medical Director Dr. Sherif Farag brings more than 30 years of experience to the Stem Cell Transplant and Cellular Therapy Institute. His background includes all areas of hematological cancers, transplantation and cellular therapies.

Previously, Dr. Farag was the director of the Bone Marrow and Blood Stem Cell Transplantation and Immune Cell Therapy Program and served as Professor of Medicine in Hematology and Oncology at Indiana University. He was also the medical director for the Blood and Bone Marrow Transplant Laboratory at The Ohio State University.

Dr. Farag has a deep commitment to advancing transplantation and cellular therapy research — with more than 100 peer-reviewed medical publications and a strong record of funding by the National Institutes of Health. He is a member of the American Society of Transplantation and Cellular Therapy, the American Society of Hematology and the American Society of Clinical Oncology.

Treatment Options

Treatment options include blood stem cell transplant and CAR T-cell therapy. Learn more below.

Blood Stem Cell Transplant

What is a blood stem cell?

These special cells generate most of the body’s blood and immune cells. They mostly live in bone marrow — the spongy tissue inside our bones — and circulate in the blood.

What is a blood stem cell transplant?

This medical procedure is often the only potentially curative option for people diagnosed with some cancers and other life-threatening diseases.

Autologous stem cell transplants use a patient’s own previously collected stem cells to replace stem cells destroyed by high-dose chemotherapy. Hematologist oncologists (doctors who specialize in blood diseases and cancers) typically recommend autologous transplants for select cancers still sensitive to chemotherapy at lower doses.

Allogeneic stem cell transplants replace a patient’s stem and immune cells with healthy stem cells from a donor. When cancer is resistant to chemotherapy, an allogeneic transplant can provide an immunological response against the patient's cancer.

What conditions are transplants used for?

Blood stem cell transplants can help treat blood cancers such as:

Leukemia and Related Disorders

  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic lymphocytic leukemia (CLL)
  • Chronic myelogenous leukemia (CML)
  • Myelodysplastic syndromes (MDS)
  • Myelofibrosis
  • Chronic myelomonocytic leukemia (CMML)

Lymphoma

  • Hodgkin Lymphoma (HL)
  • Non-Hodgkin Lymphoma (NHL)
  • Waldenström’s macroglobulinemia (WM)

Other

  • Aplastic anemia
  • Thalassemia
  • Auto-immune disease
  • Paroxysmal nocturnal hemoglobinuria (PNH)
  • Hemophagocytic lymphohistiocytosis (HLH)
  • Sickle cell disease
  • Immunodeficiency syndromes
  • Germ cell tumors (including testicular and some ovarian cancers)

Plasmacytic

  • Amyloidosis
  • Multiple myeloma

CAR T-Cell Therapy

What is CAR T-cell therapy?

Chimeric antigen receptor (CAR) T-cell therapy is a personalized treatment that engineers a patient’s own immune system to more effectively target cancer.

Certain immune system cells, called T-cells, can potentially identify and remove cancer cells in the body.

CAR T-cell therapy inserts a new gene into T-cells collected from the blood — improving their ability to target cancer cells. The modified cells (called CAR T-cells) are then infused into a patient after chemotherapy to begin fighting cancer.

What conditions does CAR T-cell therapy treat?

CAR T-cell therapy is currently approved for treatment of blood cancers, including:

  • Leukemia
    • Acute lymphoblastic leukemia (ALL)
    • Chronic lymphocytic leukemia (CLL)
  • Non-Hodgkin lymphoma (NHL)
    • Diffuse large B-cell lymphoma (DLBCL)
    • Follicular lymphoma
    • Mantle cell lymphoma
  • Multiple myeloma

The Patient Journey

Stem cell transplant patient journey

1. Evaluation

Your care team will decide if stem cell transplantation or CAR T-cell therapy is right for you.

2. Preparation

A nurse coordinator will work with your insurance provider and help schedule appointments.

3. Collection

Stem cells are collected from your bloodstream or from a donor.

4. Storage

Collected stem cells may be infused fresh or be frozen in the laboratory until ready for infusion.

5. Treatment

You will be admitted for chemotherapy, followed by stem cell infusion.

6. Recovery

You will remain in hospital until your blood cell counts return to normal.

7. Monitoring

After release, our team will continue to monitor you for side effects or infection.

Research

Stem cell research icon

An essential part of lifesaving stem cell transplant procedures is preventing complications and making them safer.

Dr. Farag and his team have published breakthrough research on reducing the risk of acute graft-versus-host disease (GVHD) — a severe side effect that can affect more than 30 percent of transplant patients.

The Institute also includes research personnel dedicated to improving treatment for hematologic malignancies.

Community MD Anderson Partnership

Community Health Network MD Anderson Cancer CenterThrough our partnership with MD Anderson Cancer Center, the Stem Cell Transplant and Cellular Therapy Institute is connected to one of the largest and most advanced facilities in the world for stem cell transplants. The partnership represents a full clinical and operational integration of Community’s cancer services with MD Anderson across all of Community’s sites of cancer care.

MD Anderson’s clinicians perform more than 850 stem cell transplant procedures for both adults and children each year, surpassing any other center in the nation, and it is recognized as a specialized center for stem cell transplants by the National Marrow Donor Program.

Contact Us

If you’re a patient looking for more information, or a physician looking to refer a patient, call the Stem Cell Transplant and Cellular Therapy Institute at:

765-776-3500, option 2

Stem Cell Transplant and Cellular Therapy Institute
Community MD Anderson Cancer Center – Kokomo
3500 S Lafountain Street, Kokomo, IN 46902